Taurine has strong antioxidant effects, which are mainly achieved through three aspects: firstly, taurine is an important endogenous antioxidant that can scavenge free radicals and lipid peroxides; Secondly, taurine can participate in the redox reaction process, and the amino groups in its molecules can bind with oxidants to inhibit oxidative stress caused by oxidants; Thirdly, taurine can also reduce the damage caused by oxidative stress to lipid membranes through its stabilizing effect on cell membranes.
Studies have shown that taurine can inhibit the cytotoxic effects of hypochlorous acid (HClO), and taurine can produce taurine chloramine (TauCl). TauCl can protect tissues and organs from the cytotoxic effects of peroxides by activating the surrounding macrophage nuclear factor E2 related factor 2/antioxidant response element (Nrf2/ARE) signaling pathway. In addition, taurine can reduce mitochondrial production of superoxide, thereby reducing oxidative stress damage.
《Taurine ameliorates cellular senescence associated with an increased hydrogen sulfide and a decreased hepatokine, IGFBP-1, in CCl4-induced hepatotoxicity in mice》 2025 年 6 月
发表平台：《Redox Biology》
关键结论：福井县立大学的研究团队研究指出，通过减轻细胞衰老、促进硫化氢（H2S）生成，以及抑制IGFBP-1表达，牛磺酸展现出了保护慢性肝损伤的强大潜力。
