Taurine is highly present in neutrophils and monocytes, and can react with lysine to produce TauCl. It not only has a direct antioxidant effect, but also reduces the production of inflammatory mediators, playing an anti-inflammatory role. TauCl reduces nuclear factor B activity through the NF kB signaling pathway and decreases the expression of its target genes monocyte chemoattractant protein-1 (MCP-1) and macrophage inflammatory protein-2 (MIP-2), ultimately reducing the secretion of inflammatory mediators NO, TNF - α, prostaglandin E2 (PGE2), IL-6, IL-8, and preventing the occurrence of chronic inflammation.
《牛磺酸消炎抗氧化机理及其在幼龄动物中的应用》 2015年
发表平台：《动物营养学报》
关键结论：牛磺酸通过雷帕霉素靶蛋白(mTOR)信号通路促进肠黏膜修复，通过抑制Toll样受体4(TLR4)信号通路缓解肠黏膜炎症反应，通过瞬时受体电位通道M2(TRPM2)离子通道改善细胞线粒体生理功能。展现了牛磺酸有消炎抗氧化生物学功能。
