Research on taurine in regulating cardiovascular function and lowering blood pressure

Hypertension is currently one of the major public health issues affecting human health worldwide, with an estimated 20% of the population affected by hypertension. Taurine plays an important role in regulating cardiovascular function, especially in lowering blood pressure, which has accumulated significant research evidence.


《Taurine and Its Derivatives: Analysis of the Inhibitory Effect on Platelet Function and Their Antithrombotic Potential》 2022 年 1 月

发表平台:美国国立医学图书馆(PubMed,J Clin Med期刊)

关键结论:牛磺酸及其衍生物(如牛磺酸氯胺)可抑制血小板聚集和血栓形成,通过降低血小板内钙浓度、抑制环氧酶-1(COX-1)活性及血栓素 A2 生成。


《Taurocholic acid ameliorates hypertension through the activation of TGR5 in the hypothalamic paraventricular nucleus》 2024年4月

发表平台:Food and Function

关键结论:研究发现,富含牛磺酸的饮食可增加牛磺酸结合的胆酸的产生,这些胆酸具有降压作用。通过牛磺酸胆酸TCA在PVN中的微量注射,研究发现牛磺酸胆酸TCA处理显著降低了SHR的血压,减少了血浆去甲肾上腺素水平,并改善了心肌细胞形态。

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